Saturday 7 June 2014

The Case of Miss C., the Woman Who Felt No Pain

The Case of Miss C., the Woman Who Felt No Pain

The best documented of all cases of congenital insensitivity to pain is Miss C., a young Canadian girl who was a student at McGill University in Montreal.... The young lady was highly intelligent and seemed normal in every way except that she had never felt pain. As a child, she had bitten off the tip of her tongue while chewing food, and had suffered third-degree burns after kneeling on a radiator to look out of the window.... She felt no pain when parts of her body were subjected to strong electric shock, to hot water at temperatures that usually produce reports of burning pain, or to a prolonged ice-bath. Equally astonishing was the fact that she showed no changes in blood pressure, heart rate, or respiration when these stimuli were presented. Furthermore, she could not remember ever sneezing or coughing, the gag reflex could be elicited only with great difficulty, and corneal reflexes (to protect the eyes) were absent. A variety of other stimuli, such as inserting a stick up through the nostrils, pinching tendons, or injections of histamine under the skin—which are normally considered as forms of torture—also failed to produce pain.
Miss C. had severe medical problems. She exhibited pathological changes in her knees, hip, and spine, and underwent several orthopaedic operations. The surgeon attributed these changes to the lack of protection to joints usually given by pain sensation. She apparently failed to shift her weight when standing, to turn over in her sleep, or to avoid certain postures, which normally prevent inflammation of joints....
Miss C. died at the age of twenty-nine of massive infections ... and extensive skin and bone trauma.
(From The Challenge of Pain, pp. 16–17, by Ronald Melzack and Patrick D. Wall, 1982, London: Penguin Books Ltd. Copyright © Ronald Melzack and Patrick D. Wall, 1982.)

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